What Drug Class Is Atropine Sulfate?

When should Atropine not be given?

Atropine should be avoided with bradycardia caused by hypothermia and, in most cases, it will not be effective for Mobitz type II/Second-degree block type 2 or complete heart block..

What is atropine used for in emergency situations?

Although atropine treats bradycardia (slow heart rate) in emergency settings, it can cause paradoxical heart rate slowing when given at very low doses (i.e. <0.5 mg), presumably as a result of central action in the CNS.

Is atropine a vasodilator?

Conclusion: Atropine showed significant vasodilation effect which may derive, in part, from endothelium. Besides, atropine could inhibit the receptor-mediated Ca2+ -influx and Ca2+ -release, which was inferred to the mechanism of atropine on vasodilation.

Does atropine increase blood pressure?

However, when given by itself, atropine does not exert a striking or uniform effect on blood vessels or blood pressure. Systemic doses slightly raise systolic and lower diastolic pressures and can produce significant postural hypotension.

What is the main action of atropine sulphate?

Mechanism of action. The most important therapeutic action of atropine is the inhibition of smooth muscle and glands innervated by postganglionic cholinergic nerves. It also has central nervous system activity, which may be stimulating or depressing depending upon the dose.

Why is atropine given?

Atropine is used to help reduce saliva, mucus, or other secretions in your airway during a surgery. Atropine is also used to treat spasms in the stomach, intestines, bladder, or other organs. Atropine is sometimes used as an antidote to treat certain types of poisoning.

What is the antidote for atropine sulfate?

Physostigmine, given as an atropine antidote by slow intravenous injection of 1 to 4 mg (0.5 to 1 mg in pediatric populations), rapidly abolishes delirium and coma caused by large doses of atropine.

Are atropine drops safe?

It is important for parents and children to understand that atropine treatment works to slow down myopia progression but does not improve the vision as with orthokeratology. However, the risks associated with atropine treatment are relatively low and the benefits may last long term.

What is atropine sulfate?

Atropine Sulfate Injection is an antimuscarinic agent used to treat bradycardia (low heart rate), reduce salivation and bronchial secretions before surgery, as an antidote for overdose of cholinergic drugs or mushroom poisoning.

Is atropine a narcotic?

What is diphenoxylate and atropine, and how does it work (mechanism of action)? Lomotil is a combination of two drugs, diphenoxylate and atropine. It is used to treat acute diarrhea (diarrhea of limited duration). Diphenoxylate is a man-made narcotic chemically related to meperidine (Demerol).

Is atropine sulfate a controlled drug?

Controlled Substance: Diphenoxylate HCl and atropine sulfate tablets are classified as a Schedule V controlled substance by federal regulation. Diphenoxylate hydrochloride is chemically related to the narcotic analgesic meperidine.

Does atropine slow heart rate?

Atropine has complex effects on heart rate: At low doses, atropine blocks M1 acetylcholine receptors in the parasympathetic ganglion controlling the SA node. This decreases heart rate (Bernheim 2004). At higher doses, atropine also blocks M2 acetylcholine receptors on the myocardium itself.

Does atropine cause blurred vision?

Ocular Adverse Reactions. Eye pain and stinging occurs upon instillation of atropine sulfate ophthalmic solution. Other commonly occurring adverse reactions include, blurred vision, photophobia, superficial keratitis and decreased lacrimation.

What are the contraindications of atropine?

The following conditions are contraindicated with this drug….Conditions:myasthenia gravis.a skeletal muscle disorder.high blood pressure.chronic heart failure.a change in saliva secretion.reflux esophagitis.or inflammation of the esophagus from backflow of stomach acid.hiatal hernia.More items…

What is the drug atropine used for?

Atropine is a prescription medicine used to treat the symptoms of low heart rate (bradycardia), reduce salivation and bronchial secretions before surgery or as an antidote for overdose of cholinergic drugs or mushroom poisoning.